Chindia Alert: You’ll be Living in their World Very Soon
aims to alert you to the threats and opportunities that China and India present. China and India require serious attention; case of ‘hidden dragon and crouching tiger’.
Without this attention, governments, businesses and, indeed, individuals may find themselves at a great disadvantage sooner rather than later.
The POSTs (front webpages) are mainly 'cuttings' from reliable sources, updated continuously.
The PAGEs (see Tabs, above) attempt to make the information more meaningful by putting some structure to the information we have researched and assembled since 2006.
Six animals inoculated with vaccine candidate then exposed to virus did not catch Covid-19 after 28 days
Up to 60 million doses could be produced by Serum Institute of India this year
Microbiologist Elisa Granato gets an injection on Thursday as part of the first human trials in Britain for a potential coronavirus vaccine. Photo: University of Oxford via AP
A leading candidate for a Covid-19 vaccine has shown promising results in animal trials, and is expected to see mass production in India within months.
The Serum Institute of India, the world’s largest maker of vaccines by volume, said on Tuesday that it plans this year to produce up to 60 million doses of a potential vaccine developed by the University of Oxford, which is under clinical trial in Britain.
While the vaccine candidate, called “ChAdOx1 nCoV-19”, is yet to be proven to work against Covid-19, Serum decided to start manufacturing it as it had shown success in animal trials and had progressed to tests on humans, Serum Chief Executive Adar Poonawalla said.
Six rhesus macaque monkeys were inoculated with the vaccine candidate at the National Institutes of Health’s Rocky Mountain Laboratory in Montana last month, according to The New York Times.
Covid-19 vaccine trial starts in Oxford, but remdesivir treatment reportedly flops in China tests
The subjects were exposed afterwards to large quantities of the novel coronavirus, but all six remained healthy after more than 28 days, the newspaper reported, citing researcher Vincent Munster, who conducted the test.
More than 3 million people have been reported to be infected globally and over 210,000 have died from Covid-19, the respiratory disease caused by the coronavirus.
“They are a bunch of very qualified, great scientists [at Oxford] … That’s why we said we will go with this and that’s why we are confident,” Poonawalla told Reuters in a phone interview.
“Being a private limited company, not accountable to public investors or bankers, I can take a little risk and sideline some of the other commercial products and projects that I had planned in my existing facility,” Poonawalla said.
Bill Gates hopes his virus vaccine ‘manufacturing within a year’
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As many as 100 potential Covid-19 candidate vaccines are now under development by biotech and research teams around the world, and at least five of these are in preliminary testing in people in what are known as phase one clinical trials.
Poonawalla said he hoped trials of the Oxford vaccine, due to finish in about September, would be successful. Oxford scientists said last week the main focus of initial tests was to ascertain not only whether the vaccine worked but that it induced good immune responses and no unacceptable side effects.
Serum, owned by the Indian billionaire Cyrus Poonawalla, plans to make the vaccine at its two manufacturing plants in the western city of Pune, aiming to produce up to 400 million doses next year if all goes well, Poonawalla said.
“A majority of the vaccine, at least initially, would have to go to our countrymen before it goes abroad,” he said, adding that Serum would leave it to the Indian government to decide which countries would get how much of the vaccine and when.
Rhesus macaque monkeys are often used in animal testing because of their similarity to humans. Photo: AFP
Serum envisages a price of 1,000 rupees (US$14.70) per vaccine, but governments would give it to people without charge, he said.
He said Prime Minister Narendra Modi’s office was “very closely” involved in the vaccine production and the company is hoping the government will help foot the cost of making it.
Over roughly the next five months, Serum will spend some 300 million to 400 million rupees (US$4.4 million to US$5.9 million) on making around 3-5 million doses per month, he said. “[The government] are very happy to share some risk and fund something with us, but we haven’t really pencilled anything down yet,” Poonawalla said.
Coronavirus: clinical trial begins on third vaccine candidate in China
22 Apr 2020
Serum has also partnered with the US biotech firm Codagenix and Austria’s Themis on two other Covid-19 vaccine candidates and plans to announce a fourth alliance in a couple of weeks, he said.
Serum’s board last week also agreed to invest roughly 6 billion rupees (US$8.8 billion) on making a new manufacturing unit to solely produce coronavirus vaccines, Poonawalla said.
SHANGHAI (Reuters) – China ordered on Saturday that anyone in Wuhan working in certain service-related jobs must take a coronavirus test if they want to leave the city.
The order comes after the central city, where the coronavirus emerged late last year, lifted a 70-day lockdown that all but ended the epidemic there.
People in Wuhan work in nursing, education, security and other sectors with high exposure to the public must take a nucleic acid test before leaving, the National Health Commission said in an order.
The government of Hubei province, of which Wuhan is capital, will pay for the tests, the commission said.
Since the city relaxed its lockdown restrictions people who arrived in there before Chinese New Year, when the virus was peaking in China, are allowed to go back to their homes.
People working in other sectors aiming to leave Wuhan are encouraged to take voluntary tests before going.
Within seven days of arrival at their destinations, people who can present test results showing they do not carry the virus, as well as a clean bill of health on a health app, can go back to work.
Everyone else will have to spend 14 days in quarantine before returning to work.
Authorities have worked with the China’s tech giants to devise a colour-based health code system, retrieved via mobile app, that uses geolocation data and self-reported information to indicate one’s health status.
Wuhan will speed up its efforts to investigate asymptomatic coronavirus cases and confirm the presence of antibodies in people, which might suggest immunity, the commission said.
Wuhan, which accounts for 60% of infections in China and 84% of the death toll as of Saturday, has been testing inhabitants aggressively throughout the virus’ breakout and many companies had already been asking workers from the city to undergo tests before resuming work.
Wuhan revised up its death toll from the coronavirus by 1,290 on Friday, taking the city’s toll to 3,869, because of incorrect reporting, delays and omissions, especially in the chaotic early stages of the outbreak, authorities said.
China national death toll is 4,632 from 82,719 cases.
SUIFENHE, China (Reuters) – China’s northeastern border with Russia has become a frontline in the fight against a resurgence of the coronavirus epidemic as new daily cases rose to the highest in nearly six weeks – with more than 90% involving people coming from abroad.
Having largely stamped out domestic transmission of the disease, China has been slowly easing curbs on movement as it tries to get its economy back on track, but there are fears that a rise in imported cases could spark a second wave of COVID-19.
A total of 108 new coronavirus cases were reported in mainland China on Sunday, up from 99 a day earlier, marking the highest daily tally since March 5.
Imported cases accounted for a record 98. Half involved Chinese nationals returning from Russia’s Far Eastern Federal District, home to the city of Vladivostok, who re-entered China through border crossings in Heilongjiang province.
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“Our little town here, we thought it was the safest place,” said a resident of the border city of Suifenhe, who only gave his surname as Zhu.
“Some Chinese citizens – they want to come back, but it’s not very sensible, what are you doing coming here for?”
The border is closed, except to Chinese nationals, and the land route through the city had become one of few options available for people trying to return home after Russia stopped flights to China except for those evacuating people.
Streets in Suifenhe were virtually empty on Sunday evening due to restrictions of movement and gatherings announced last week, when authorities took preventative measures similar to those imposed in Wuhan, the central Chinese city where the pandemic ripping round the world first emerged late last year.
The total number of confirmed cases in mainland China now stands at 82,160 as of Sunday, and at the peak of the first wave of the epidemic on Feb 12 there were over 15,000 new cases.
Though the number of daily infections across China has dropped sharply from that peak, China has seen the daily toll creep higher after hitting a trough on March 12 because of the rise in imported cases.
Chinese cities near the Russian frontier are tightening border controls and imposing stricter quarantines in response.
Suifenhe and Harbin, the capital of Heilongjiang, are now mandating 28 days of quarantine as well as nucleic acid and antibody tests for all arrivals from abroad.
In Shanghai, authorities found that 60 people who arrived on Aeroflot flight SU208 from Moscow on April 10 have the coronavirus, Zheng Jin, a spokeswoman for the Shanghai Municipal Health Commission, told a press conference on Monday.
Residents in Suifenhe said a lot of people had left the city fearing contagion, but others put their trust in authorities’ containment measures.
“I don’t need to worry,” Zhao Wei, another Suifenhe resident, told Reuters. “If there’s a local transmission, I would, but there’s not a single one. They’re all from the border, but they’ve all been sent to quarantine.”