Archive for ‘Ebola’

30/04/2020

Last Hong Kong governor Chris Patten asks UK to watch out for Beijing interference in city affairs

  • Patten says to watch out for any future attempts by Beijing to ‘undermine the rule of law and to corrupt the electoral process in the months ahead’
  • The plea comes as the ruling Conservative Party in Britain toughens up China policies
Chris Patten is an outspoken critic of the Chinese government’s handling of Hong Kong affairs. Photo: AFP
Chris Patten is an outspoken critic of the Chinese government’s handling of Hong Kong affairs. Photo: AFP

Britain’s last colonial governor of Hong Kong, Chris Patten, has asked the British government to watch out for Chinese attempts to interfere with the city’s affairs while the world grapples with the coronavirus pandemic.

He made the plea to Foreign Secretary Dominic Raab as the ruling Conservative Party toughens up China policies, amid what many party members see as Beijing’s deliberate failures to be transparent about the initial Covid-19 outbreaks.

The call also comes amid growing worry among Hong Kong’s pro-democracy activists, as police have rounded up dissidents and Beijing authorities have stepped up the rhetoric of national security concerns.

Patten, an outspoken critic of the Chinese government’s handling of Hong Kong affairs, said: “I hope we can … count on the British government to call out China for its breaches of the [Sino-British] Joint Declaration and to watch carefully for future attempts by Beijing to undermine the rule of law and to corrupt the electoral process in the months ahead.”

Wave of arrests of Hong Kong pro-democracy figures draws global criticism

The declaration provided for Hong Kong’s status quo until 2047.

The Foreign Office has not responded to an inquiry by the Post on Patten’s letter.

Citing their roles in unlawful protests, Hong Kong police rounded up at least 15 opposition camp activists earlier this month, including media tycoon Jimmy Lai Chee-ying and prominent barrister Martin Lee Chu-ming, known as the city’s “father of democracy”.
On Tuesday, a bipartisan group of US lawmakers wrote Secretary of State Mike Pompeo requesting that his department’s upcoming assessment of Hong Kong’s autonomy reflect a recent wave of arrests by the city’s authorities of pro-democracy activists.
Hong Kong police to respond with force to any Labour Day protests
30 Apr 2020

Patten also asked the British government to investigate the origin of the coronavirus.

“I would be grateful for your assurance that the British government will press for an expert mission to Wuhan and will encourage other countries to do the same,” he wrote, underscoring the need to “make sure that we know everything about the nature of the virus in order to fight it effectively. We also need to prevent anything similar happening in the future.”

On Wednesday, Britain’s ambassador to the US Karen Pierce backed calls for an investigation into the origins of the novel coronavirus and the response of the World Health Organisation.

“We need to learn after all these crises, just as we did after Ebola in 2014. We need to learn how we can always do things better,” she said.

The comments came after Britain’s foreign affairs parliamentary committee asked the government whether it plans to use international bodies to hold China to account over the Covid-19 pandemic.

Source: SCMP

29/03/2020

Coronavirus: pathogen could have been spreading in humans for decades, study says

  • Virus may have jumped from animal to humans long before the first detection in Wuhan, according to research by an international team of scientists
  • Findings significantly reduce the possibility of the virus having a laboratory origin, director of the US National Institute of Health says
An international team of scientists say the coronavirus may have jumped from animal to humans long before the first detection in China. Photo: AP
An international team of scientists say the coronavirus may have jumped from animal to humans long before the first detection in China. Photo: AP
The coronavirus that causes Covid-19 might have been quietly spreading among humans for years or even decades before the sudden outbreak that sparked a global health crisis, according to an investigation by some of the world’s top virus hunters.
Researchers from the United States, Britain and Australia looked at piles of data released by scientists around the world for clues about the virus’ evolutionary past, and found it might have made the jump from animal to humans long before the first detection in the central China city of Wuhan.
Though there could be other possibilities, the scientists said the coronavirus carried a unique mutation that was not found in suspected animal hosts, but was likely to occur during repeated, small-cluster infections in humans.

The study, conducted by Kristian Andersen from the Scripps Research Institute in California, Andrew Rambaut from the University of Edinburgh in Scotland, Ian Lipkin from Columbia University in New York, Edward Holmes from the University of Sydney, and Robert Garry from Tulane University in New Orleans, was published in the scientific journal Nature Medicine on March 17.

Dr Francis Collins, director of the US National Institute of Health, who was not involved in the research, said the study suggested a possible scenario in which the coronavirus crossed from animals into humans before it became capable of causing disease in people.

“Then, as a result of gradual evolutionary changes over years or perhaps decades, the virus eventually gained the ability to spread from human to human and cause serious, often life-threatening disease,” he said in an article published on the institute’s website on Thursday.

In December, doctors in Wuhan began noticing a surge in the number of people suffering from a mysterious pneumonia. Tests for flu and other pathogens returned negative. An unknown strain was isolated, and a team from the Wuhan Institute of Virology led by Shi Zhengli traced its origin to a bat virus found in a mountain cave close to the China-Myanmar border.

The two viruses shared more than 96 per cent of their genes, but the bat virus could not infect humans. It lacked a spike protein to bind with receptors in human cells.

Coronaviruses with a similar spike protein were later discovered in Malayan pangolins
by separate teams from Guangzhou and Hong Kong, which led some researchers to believe that a recombination of genomes had occurred between the bat and pangolin viruses.
Doctors in Wuhan began noticing a surge in the number of people suffering from a mysterious pneumonia in December. Photo: Handout
Doctors in Wuhan began noticing a surge in the number of people suffering from a mysterious pneumonia in December. Photo: Handout
But the new strain, or SARS-Cov-2, had a mutation in its genes known as a polybasic cleavage site that was unseen in any coronaviruses found in bats or pangolins, according to Andersen and his colleagues.

This mutation, according to separate studies by researchers from China, France and the US, could produce a unique structure in the virus’ spike protein to interact with furin, a widely distributed enzyme in the human body. That could then trigger a fusion of the viral envelope and human cell membrane when they came into contact with one another.

Some human viruses including HIV and Ebola have the same furin-like cleavage site, which makes them contagious.

It is possible that the mutation happened naturally to the virus on animal hosts. Sars (severe acute respiratory syndrome) and Mers (Middle East respiratory syndrome), for instance, were believed to have been direct descendants of species found in masked civets and camels, which had a 99 per cent genetic similarity.

There was, however, no such direct evidence for the novel coronavirus, according to the international team. The gap between human and animal types was too large, they said, so they proposed another alternative.

“It is possible that a progenitor of SARS-CoV-2 jumped into humans, acquiring the genomic features described above through adaptation during undetected human-to-human transmission,” they said in the paper.

“Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases to trigger the surveillance system that detected it.”

They said also that the most powerful computer models based on current knowledge about the coronavirus could not generate such a strange but highly efficient spike protein structure to bind with host cells.

The study had significantly reduced, if not ruled out, the possibility of a laboratory origin, Collins said.

“In fact, any bioengineer trying to design a coronavirus that threatened human health probably would never have chosen this particular conformation for a spike protein,” he said.

The findings by Western scientists echoed the mainstream opinion among Chinese researchers.

Zhong Nanshan, who advises Beijing on outbreak containment policies, had said on numerous occasions that there was growing scientific evidence to suggest the origin of the virus might not have been in China.

“The occurrence of Covid-19 in Wuhan does not mean it originated in Wuhan,” he said last week.

A doctor working in a public hospital treating Covid-19 patients in Beijing said numerous cases of mysterious pneumonia outbreaks had been reported by health professionals in several countries last year.

Re-examining the records and samples of these patients could reveal more clues about the history of this worsening pandemic, said the doctor, who asked not to be named due to the political sensitivity of the issue.

“There will be a day when the whole thing comes to light.”

Source: SCMP

01/02/2020

Coronavirus declared global health emergency by WHO

The new coronavirus has been declared a global emergency by the World Health Organization, as the outbreak continues to spread outside China.

“The main reason for this declaration is not what is happening in China but what is happening in other countries,” said WHO chief Tedros Adhanom Ghebreyesus.

The concern is that it could spread to countries with weaker health systems.

Meanwhile, the US has told its citizens not to travel to China.

The state department issued a level four warning – having previously urged Americans to “reconsider” travel to China – and said any citizens in China “should consider departing using commercial means”.

China has said it will send charter plans to bring back Hubei province residents who are overseas “as soon as possible”.

A foreign ministry spokesman said this was because of the “practical difficulties” Chinese citizens have faced abroad. Hubei is where the virus emerged.

At least 213 people in the China have died from the virus, mostly in Hubei, with almost 10,000 cases nationally.

The WHO said there had been 98 cases in 18 other countries, but no deaths.

Most international cases are in people who had been to Wuhan in Hubei.

However in eight cases – in Germany, Japan, Vietnam and the United States – patients were infected by people who had travelled to China.

People wearing masks

Getty Coronavirus outbreak outside China
  • 18 The number of countries with cases
  • 14 Cases in Thailand and Japan
  • 13 Singapore
  • 11 South Korea
  • 8 Australia and Malaysia
  • 5 France and USA

Source: WHO and local authorities

Speaking at a news conference in Geneva, Dr Tedros described the virus as an “unprecedented outbreak” that has been met with an “unprecedented response”.

He praised the “extraordinary measures” Chinese authorities had taken, and said there was no reason to limit trade or travel to China.

“Let me be clear, this declaration is not a vote of no confidence in China,” he said.

But various countries have taken steps to close borders or cancel flights, and companies like Google, Ikea, Starbucks and Tesla have closed their shops or stopped operations.

The US Commerce Secretary, Wilbur Ross, has said the outbreak could “accelerate the return of jobs to North America”.

Presentational grey line

Preparing other countries

Analysis box by James Gallagher, health and science correspondent

What happens if this virus finds its way into a country that cannot cope?

Many low- and middle-income countries simply lack the tools to spot or contain it. The fear is it could spread uncontrollably and that it may go unnoticed for some time.

Remember this is a disease which emerged only last month – and yet there are already almost 10,000 confirmed cases in China.

The 2014 Ebola outbreak in West Africa – the largest in human history – showed how easily poorer countries can be overwhelmed by such outbreaks.

And if novel coronavirus gets a significant foothold in such places, then it would be incredibly difficult to contain.

We are not at that stage yet – 99% of cases are in China and the WHO is convinced the country can control the outbreak there.

But declaring a global emergency allows the WHO to support lower- and middle-income countries to strengthen their disease surveillance – and prepare them for cases.

Presentational grey line

How unusual is this declaration?

The WHO declares a Public Health Emergency of International Concern when there is “an extraordinary event which is determined… to constitute a public health risk to other states through the international spread of disease”.

It has previously declared five global public health emergencies:

  • Swine flu, 2009 – The H1N1 virus spread across the world in 2009, with death toll estimates ranging from 123,000 to 575,400
  • Polio, 2014 – Although closer than ever to eradication in 2012, polio numbers rose in 2013
  • Zika, 2016 – The WHO declared Zika a public health emergency in 2016 after the disease spread rapidly through the Americas
  • Ebola, 2014 and 2019 – The first emergency over the virus lasted from August 2014 to March 2016 as almost 30,000 people were infected and more than 11,000 died in West Africa. A second emergency was declared last year as an outbreak spread in DR Congo

Media caption Inside the US laboratory developing a coronavirus vaccine

How is China handling the outbreak?

A confirmed case in Tibet means the virus has reached every region in mainland China. According to the country’s National Health Commission, 9,692 cases have tested positive.

The central province of Hubei, where nearly all deaths have occurred, is in a state of lockdown. The province of 60 million people is home to Wuhan, the heart of the outbreak.

The city has effectively been sealed off and China has put numerous transport restrictions in place to curb the spread of the virus.

Coronavirus cases have spread to every province in China. There are now 7711 cases compared to 291 on 20 Jan. Hubei province has more than 4500 cases.
People who have been in Hubei are also being told to work from home until it is considered safe for them to return.

The virus is affecting China’s economy, the world’s second-largest, with a growing number of countries advising their citizens to avoid all non-essential travel to the country.

How is the world responding?

Voluntary evacuations of hundreds of foreign nationals from Wuhan are under way.

The UK, Australia, South Korea, Singapore and New Zealand are expected to quarantine all evacuees for two weeks to monitor them for symptoms and avoid contagion.

Australia plans to quarantine its evacuees on Christmas Island, 2,000km (1,200 miles) from the mainland in a detention centre that has been used to house asylum seekers.

In other recent developments:

  • Italy suspended flights to China after two Chinese tourists in Rome were diagnosed with the virus; earlier 6,000 people on board a cruise ship were temporarily barred from disembarking
  • In the US, Chicago health officials have reported the first US case of human-to-human transmission. Around 200 US citizens have been flown out of Wuhan and are being isolated at a Californian military base for at least 72 hours
  • Russia has decided to close its 4,300km (2,670-mile) far-eastern border with China
  • Two flights to Japan have already landed in Tokyo. Japan has now raised its infectious disease advisory level for China
  • Some 250 French nationals have been evacuated from Wuhan
  • India has confirmed its first case of the virus – a student in the southern state of Kerala who was studying in Wuhan
  • Israel has barred all flight connections with China
  • Papua New Guinea has banned all visitors from “Asian ports”
  • North Korea will suspend all flights and trains to and from China, said the British ambassador to North Korea

Source: The BBC

23/01/2020

Coronavirus: Wuhan shuts public transport over outbreak

Wuhan, a Chinese city of eleven million people, has temporarily shut down its public transport as it tries to halt the outbreak of a new strain of virus.

Those living in the city have been advised not to leave, in a week when millions of Chinese are travelling for the upcoming Lunar New Year holiday.

The respiratory illness has spread to other parts of China, with some cases in other countries including the US.

There are more than 500 confirmed cases and 17 people have died.

Known for now as 2019-nCoV, the virus is understood to be a new strain of coronavirus not previously identified in humans. The Sars (severe acute respiratory syndrome) virus that killed nearly 800 people globally in the early 2000s was also a coronavirus, as is the common cold.

All the fatalities so far have been in Hubei, the province around Wuhan.

Meanwhile, after a day of discussions in Geneva, the World Health Organization’s (WHO) emergency committee has announced it will not yet declare a “global emergency” over the new virus.

Director general Dr Tedros Ghebreyesus said more information was needed about the spread of the infection. The committee of health experts will meet again on Thursday.

A global emergency is the highest level of alarm the WHO can sound and has previously been used in response to swine flu, Zika virus and Ebola.

What measures have been announced?

From Thursday, all flights and passenger train services out of Wuhan have been stopped.

Bus, subway and ferry services all shut down from 10:00 local time (02:00 GMT).

A special command centre in Wuhan set up to contain the virus said the move was meant to “resolutely contain the momentum of the epidemic spreading”.

Map of Wuhan transportThose living in Wuhan had already been told to avoid crowds and minimise public gatherings.

State news agency Xinhua said tourist attractions and hotels in the city had been told to suspend large-scale activities while libraries, museums and theatres were cancelling exhibitions and performances.

A Lunar New Year prayer-giving ceremony at the city’s Guiyuan Temple, which attracted 700,000 people last year, has also been cancelled.

The hashtag “Wuhan is sealed off” was trending on Chinese social media website Weibo.

One user said worries about food and disinfectant made it feel like “the end of the world”, while another said they were on the “verge of tears” when Chinese officials announced the shut-down.

The WHO’s Dr Ghebreyesus described the latest measures as “very strong” and said they would “not only control the outbreak, they will minimise spread internationally”.

Chinese officials said the country was now at the “most critical stage” of prevention and control.

“Basically, do not go to Wuhan. And those in Wuhan please do not leave the city,” said National Health Commission vice-minister Li Bin in one of the first public briefings since the beginning of the outbreak.

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Like shutting down London before Christmas

By James Gallagher, BBC health and science correspondent

Wuhan is starting to look like a city in quarantine.

Officials had already warned residents not to leave the city and visitors not to come.

Now the reported public transport ban – which includes flights – slams many of the routes in and out of the city shut.

A man wears a mask on the subway on January 22, 2020 in Wuhan, Hubei province, ChinaImage copyright GETTY IMAGES
Image caption Subways in Wuhan will be temporarily shut

It is a significant attempt to stop the spread of this new virus, which we now know can spread from person to person.

Limiting transport will cut the chance of the virus reaching other cities in China and other countries around the world.

This all comes just as millions of people are travelling across China for the week-long holiday that is Lunar New Year.

If you’re struggling for context – imagine shutting down London in the week before Christmas.

The big question left is the roads – and whether any of Wuhan’s 11 million inhabitants will be able to simply drive away.

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What’s the picture globally?

Officials in Hong Kong reported the territory’s first two cases on Wednesday and one case was reported in the nearby city of Macau.

The patient in Macau is said to be a businesswoman who arrived from Wuhan over the weekend.

The first US case was confirmed on Tuesday. President Donald Trump said the situation was “totally under control” and that he trusted the information being provided by Chinese authorities.

Map: Confirmed cases in China and around the world
There have been three cases in Thailand, one in Korea, one in Japan and one in Taiwan.

Although only about 500 cases have been confirmed, calculations by scientists at the MRC Centre for Global Infectious Disease Analysis at Imperial College London suggest there are 4,000 people sick with the virus in Wuhan.

What do we know about the virus?

The virus originated in a seafood market in Wuhan that “conducted illegal transactions of wild animals”, authorities said. The market has since been shut down.

There is also evidence of human to human transmission with the new virus spreading to family members and healthcare workers.

But understanding how easily and how often the virus spread between people is one of the major outstanding questions in this outbreak.

The virus infects the lungs and symptoms start with a fever and cough. It can progress to shortness of breath and breathing difficulties.

Source: The BBC

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