Chindia Alert: You’ll be Living in their World Very Soon
aims to alert you to the threats and opportunities that China and India present. China and India require serious attention; case of ‘hidden dragon and crouching tiger’.
Without this attention, governments, businesses and, indeed, individuals may find themselves at a great disadvantage sooner rather than later.
The POSTs (front webpages) are mainly 'cuttings' from reliable sources, updated continuously.
The PAGEs (see Tabs, above) attempt to make the information more meaningful by putting some structure to the information we have researched and assembled since 2006.
An antibody engineered from the animal’s immune system was found to neutralise the virus that causes Covid-19
American and Belgian researchers hope the discovery may help protect humans from the deadly illness
Winter the llama (front) lives on a farm operated by Ghent University’s Vlaams Institute for Biotechnology. Photo: Tim Coppens
A Belgian llama could hold the key to producing an antibody that neutralises the coronavirus that causes Covid-19.
More studies and clinical trials are needed to see if it can be used in humans to treat Covid-19, but the team of American and Belgian scientists who engineered the antibody said they were encouraged by their preliminary findings, which will be published in the journal Cell next week.
Jason McLellan, from the University of Texas at Austin and co-author of the study, described it as one of the “first antibodies known to neutralise Sars-CoV-2”, the official name for the virus.
“With antibody therapies, you’re directly giving somebody the protective antibodies and so, immediately after treatment, they should be protected,” he wrote in a press release.
“The antibodies could also be used to treat somebody who is already sick to lessen the severity of the disease.”
Winter the llama produced antibodies that proved effective against the Sars-CoV-2 virus. Photo: Tim Coppens
The scientists have been working on coronaviruses – including severe acute respiratory syndrome (Sars) and Middle East respiratory syndrome (Mers) – for years.
In 2016 they injected the llama, named Winter, with Sars and Mers in the hope of developing a treatment for the diseases.
“I thought this would be a small side project,” said Dorien De Vlieger from Ghent University in Belgium, who helped to isolate antibodies against coronaviruses from the llamas.
China’s race for a Covid-19 vaccine hits a hurdle – no outbreak at home
1 May 2020
“Now the scientific impact of this project became bigger than I could ever expect. It’s amazing how unpredictable viruses can be.”
A llama’s immune system produces two types of antibodies when it detects pathogens, one similar to human antibodies and one that is about a quarter of the size.
The antibodies produced by Winter were found to be effective in targeting the Sars virus’s spike protein, which allows it to bind to human cells.
Chinese firm ready to make 100 million Coronavirus vaccine doses if trials are successful
This year they decided to test the antibodies Winter had produced during the Sars experiment to see if it could prove effective against Covid-19.
Although it did bind itself to the Sars-CoV-2 virus it did so “weakly”, so the team then linked two copies of the antibody together to make it bind more effectively.
Oxford vaccine effective in monkeys, heading for mass production in India
30 Apr 2020
“That was exciting to me because I’d been working on this for years. But there wasn’t a big need for a coronavirus treatment then. This was just basic research,” said Daniel Wrapp from the University of Texas, a co-author of the study.
The smaller type of antibodies produced by llamas, called single-domain antibodies or nanobodies, can be used in an inhaler, according to Wrapp.
“That makes them potentially really interesting as a drug for a respiratory pathogen because you’re delivering it right to the site of infection,” said Wrapp.
Researchers created an antibody dubbed VHH-72Fc (blue) that binds tightly to the Sars-CoV-2 spike protein (pink, green and orange), blocking the virus from infecting cells. Photo: University of Texas at Austin
The researchers are preparing for more trials with hamsters or primates to further test the antibody, before taking it to human trials.
The main subject of the study, Winter the llama, is now four years old and lives on a farm operated by Ghent University’s Vlaams Institute for Biotechnologym which said it has around 130 other llamas and alpacas at the facility.
TAIPEI (Reuters) – Taiwan waded into the hotly contested politics of the Pacific on Wednesday, donating face masks and thermal cameras to its four diplomatic allies there to combat the coronavirus in a region where China is challenging traditional power of the United States.
The small developing nations lie in the highly strategic waters of the Pacific, dominated since World War Two by the United States and its friends, who have been concerned over China’s moves to expand its footprint there.
Democratic Taiwan has faced intense pressure from China, which claims the island as its territory with no right to state-to-state ties, and is bent on wooing away its few allies.
Taiwan has only 15 formal allies left worldwide after losing two Pacific nations, the Solomon Islands and Kiribati, to China in September.
Beijing has ramped up its diplomatic push into the Pacific, pledging virus aid and medical advice.
In its own aid programme, Taiwan has donated 16 million masks to countries around the world.
“We are a very small country, so it’s easier for us to work with Taiwan than mainland China,” Neijon Edwards, the Marshall Islands ambassador to Taiwan, told Reuters at the donation ceremony in Taipei.
China has been too overbearing, she added.
“It’s pressing too much, and it’s been trying to come to the Marshall Islands, several times, but up to this time we haven’t even opened the door yet.”
While the masks presented at the ceremony are going to Taiwan’s Pacific allies, all its 15 global allies are sharing the thermal cameras.
“Today’s ceremony once again shows that Taiwan is taking concrete actions not only to safeguard the health of Taiwanese people but also to contribute to global efforts to contain COVID-19,” said Foreign Minister Joseph Wu.
Though Pacific Island states offer little economically to either China and Taiwan, their support is valued in global forums such as the United Nations and as China seeks to isolate Taiwan.
China has offered to help developing countries including those of the Pacific, and many see Chinese lending as the best bet to develop their economies.
But critics say Chinese loans can lead countries into a “debt trap”, charges China has angrily rejected.
The debt issue was a serious problem and would only lead to the spread of Chinese influence regionwide, said Jarden Kephas, the ambassador of Nauru.
“They will end up dominating or having a lot of say in those countries because of the amount of debt,” he told Reuters, wondering how the money could ever be repaid. “We are not rich countries.”
Buying and paying for meals and supplies online was already second nature for many Chinese before the Covid-19 lockdown
The supply and delivery networks that were already in place were able to work with the authorities in cities like Wuhan
China’s established home delivery system played an important role in getting food and other necessities to residents during the Wuhan lockdown. Photo: EPA-EFE
When Liu Yilin, a retired middle schoolteacher in Wuhan, first heard rumours of a
and shoppers flooded to the markets and malls to snap up supplies.
But as time went on and with residents banned from leaving their homes, he became increasingly concerned about getting hold of fresh supplies of vegetables, fruit and meat until the nation’s vast network of delivery drivers came to the rescue.
“It was such a relief that several necessity purchasing groups organised by community workers and volunteers suddenly emerged on WeChat [a leading social media app] days after the lockdown,” Liu said. “China’s powerful home delivery service makes life much easier at a time of crisis.”
Hu Xingdou, a Beijing-based independent political economist said: “Home delivery played a very important role amid the coronavirus outbreak. To some extent, it prevented people from starving especially in cases when local governments took extreme measures to isolate people.”
According to Liu, people in Wuhan during the lockdown had to stay within their residential communities, with community workers guarding the exits.
Human contact was limited to the internet. Residents placed orders online with farmers, small merchants or supermarkets to buy daily necessities, and community workers helped distribute the goods from deliverymen.
Every morning, Liu passed a piece of paper with his name, phone number and order number to a community worker who would collect the items from a courier at the gate of the residential area.
Thanks to a high population density in urban areas, affluent labour force and people’s openness to digital life, China has built a well-developed home delivery network.
Extensive funding from technology companies has been invested in hardware infrastructure, software to improve logistics and big data and cloud computing to help predict consumers’ behaviour.
Mark Greeven, professor of innovation and strategy at IMD Business School in Lausanne, Switzerland, said: “Whether it is delivery of products, air parcels or fresh food or even medicine or materials for medical use, China has a very well developed system. Much better developed than I think almost any other places in the world.
“Well before the crisis, China had started to embrace digital technology in daily life whether it is in consumption, business, government and smart cities and use of third party payments. All of these things have been in place for a long time and the crisis tested its agility and capability to deal with peak demand.”
China’s e-commerce giants help revive sales of farm goods from Hubei
3 Apr 2020
According to e-commerce giant JD.com, demands for e-commerce and delivery services spiked during the outbreak of Covid-19, the illness caused by the new coronavirus.
It sold around 220 million items between January 20 and February 28, mainly grains and dairy products with the value of beef orders trebling and chicken deliveries quadrupling compared with a year ago.
Tang Yishen, head of JD Fresh, its fresh foods subsidiary, said: “The surge of online demand for fresh merchandise shows the pandemic helped e-commerce providers further penetrate into the life of customers. It also helped upstream farm producers to know and trust us.”
Meituan Dianping, a leading e-commerce platform, said its grocery retail service Meituan Instashopping reported a 400 per cent growth in sales from a year ago in February from local supermarkets.
The most popular items ordered between January 26 and February 8 were face masks, disinfectant, tangerines, packed fresh-cut fruits and potatoes.
The food delivery service Ele.me said that, between January 21 and February 8, deliveries of frozen food surged more than 600 per cent year on year, followed by a nearly 500 per cent growth in delivery of pet-care products. Fresh food deliveries rose by 181 per cent while drink and snack deliveries climbed by 101 per cent and 82 per cent, respectively. Ele.me is owned by Alibaba, the parent company of the South China Morning Post.
Chinese hotpot restaurant chain adapts as coronavirus fears push communal meals off the menu
E-commerce providers used the opportunity to show goodwill and improve their relationship with customers and partners, analysts say.
Sofya Bakhta, marketing strategy analyst at the Shanghai-based Daxue Consulting, said the food delivery sector had made significant headway in reducing physical contact during the outbreak.
Delivery staff left orders in front of buildings, in lifts or temporary shelters as instructed by the clients as most properties no longer allowed them inside.
Some companies also adopted more hi-tech strategies.
In Beijing, Meituan used self-driving vehicles to deliver meals to contactless pickup stations. It also offered cardboard boxes to be used as shields aimed at preventing the spread of droplets among its clients while they ate in their workplaces. In Shanghai, Ele.me employed delivery drones to serve people under quarantine in the most affected regions.
Some companies even “shared” employees to meet the growing labour demand in the food delivery industry that could not be satisfied with their ordinary workforce, Bakhta said.
More employees from restaurants, general retail and other service businesses were “loaned” to food delivery companies, which faced manpower shortages during the outbreak, according to Sandy Shen, senior research director at global consultancy Gartner.
“These arrangements not only ensured the continuity of the delivery service but also helped businesses to retain employees during the shutdown,” she said.
A delivery man takes a break between orders in Wuhan, central China, during the lockdown. Photo: AFP
Mo Xinsheng became one such “on-loan” worker after customers stopped coming to the Beijing restaurant where he worked as a kitchen assistant.
“I wanted to earn some money and meanwhile help people who are trapped at home,” said Mo, who was hired as a delivery man.
But before he could start work he had to go through lengthy health checks before he was allowed into residential compounds.
He also had to work long hours battling the wind and cold of a Beijing winter and carrying heavy loads.
“I work about 10 hours every day just to earn several thousand yuan [several hundred US dollars] a month,” he said.
“Sometimes I almost couldn’t breathe while my hands were fully loaded with packages of rice, oil and other things.
“But I know I’m doing an important job, especially at a time of crisis,” Mo said, “It was not until then that I realised people have become so reliant on the home delivery system.”
Woman uses remote control car to buy steamed buns amid coronavirus outbreak in China
The delivery system has been improved by an effective combination of private sector innovation and public sector coordination, said Li Chen, assistant professor at the Centre for China Studies at Chinese University of Hong Kong.
“[In China,] government units and the Communist Party grass roots organisations have maintained fairly strong mobilisation capabilities to cope with emergencies, which has worked well in the crisis,” he said.
However, Liu, the Wuhan resident, said prices had gone up and vegetables were three times more expensive than they had been over Lunar New Year in 2019.
“There were few varieties that we could choose from, apart from potatoes, cabbage and carrots,” he said.
“But I’m not complaining. It’s good we can still get fresh vegetables at a difficult time. Isn’t it? After all, we are just ordinary people,” he said.
GUANGZHOU, Feb. 13 (Xinhua) — Two separate research groups led by China’s top scientists said they had isolated novel coronavirus strains from samples of infected patients’ feces, but further study is needed to prove the existence of fecal-oral transmission.
Researchers from multiple organizations, including the State Key Laboratory of Respiratory Disease under Guangzhou Medical University, have successfully isolated a strain of virus from swab sample of an infected patient’s feces, said Zhao Jincun, a member of Chinese respiratory expert Zhong Nanshan’s research group, at a press conference Thursday.
The swab sample was provided by the Fifth Affiliated Hospital of Sun Yat-Sen University, said Zhao, also a professor with the laboratory.
Meanwhile, a research team led by Li Lanjuan, a renowned Chinese epidemiologist, also isolated novel coronavirus strains from stool specimens of infected patients. Three of the five feces samples tested positive, according to Wu Nanping, deputy director of the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Zhejiang University.
“We made the discoveries in the laboratory, which still need further confirmation by epidemiologists. More scientific researches are also entailed concerning the level of infectivity and whether the virus in feces was swallowed by patients or from intestinal cell proliferation, as well as its relationship with blood, sputum and the occurrence and development of diseases,” Wu said.
According to Zhao, the discovery confirmed that the patients’ feces contained the live virus, but it still lacks sufficient evidence for the existence of fecal-oral transmission.
Transmission through means of respiratory and contact remain the major routes of the novel coronavirus spreading, said Mi Feng, an official with the National Health Commission, at a press conference Thursday.
Despite digestive tract problems of some patients, either as incipient symptoms or complications, the main clinical symptoms of the disease are fever, general weakness and dry cough, Mi said, adding that the coronavirus isolated from patients’ feces is not yet illustrative to prove the change of the transmission route.
Mi said that stomach and intestine symptoms, such as diarrhea, of some patients in the early stages, the positive test for the coronavirus nucleic acid in feces samples of patients and the isolated virus from patients’ feces samples indicate the proliferation of the virus can happen in the digestive tract after infection.
Wearing masks and keeping hands clean are the most important and effective ways to avoid infections, Mi said, adding that washing hands more frequently, in the right way and disinfection of hands can reduce the risk of infection fundamentally.
Further observation and research would be needed to identify the effect and significance of transmission via the digestive tract, including fecal-oral transmission, Mi said.
India has said it will ensure the “complete isolation” of Pakistan after a suicide bomber killed 46 soldiers in Indian-administered Kashmir.
Federal Minister Arun Jaitley said India would take “all possible diplomatic steps” to cut Pakistan off from the international community.
India accuses Pakistan of failing to act against the militant group which said it carried out the attack.
This is the deadliest attack to hit the disputed region in decades.
Both India and Pakistan claim all of Muslim-majority Kashmir but only control parts of it.
An insurgency has been ongoing in Indian-administered Kashmir since the late 1980s and there has been an uptick in violence in recent years.
How will India ‘punish’ Pakistan?
India says that Jaish-e-Mohammad, the group behind the attack, has long had sanctuary in Pakistan and accuses its neighbour of failing to crack down on it.
It has called for global sanctions against the group and has said it wants its leader, Masood Azhar, to be listed as a terrorist by the UN security council.
Although India has tried to do this several times in the past, its attempts were repeatedly blocked by China, an ally of Pakistan.
Mr Jaitley set out India’s determination to hold Pakistan to account when speaking to reporters after attending a security meeting early on Friday.
He also confirmed that India would revoke Most Favoured Nation status from Pakistan, a special trading privilege granted in 1996.
Pakistan said it was gravely concerned by the bombing but rejected allegations that it was in any way responsible.
But after Prime Minister Narendra Modi said in a speech that those behind the attack would pay a “heavy price”, many analysts expect more action from Delhi.
After a 2016 attack on an Indian army base that killed 19 soldiers, Delhi said it carried out a campaign of “surgical strikes” in Pakistan-administered Kashmir, across the de facto border. But a BBC investigation found little evidence militants had been hit.
However analysts say that even if the Indian government wants to go further this time, at the moment its options appear limited due to heavy snow across the region.
How did the attack unfold?
The bomber used a vehicle packed with explosives to ram into a convoy of 78 buses carrying Indian security forces on the heavily guarded Srinagar-Jammu highway about 20km (12 miles) from the capital, Srinagar.
“A car overtook the convoy and rammed into a bus,” a senior police official told BBC Urdu.
It stands as the deadliest militant attack on Indian forces in Kashmir since the insurgency began in 1989.
The bomber is reported to be Adil Dar, a high school dropout who left home in March 2018. He is believed to be between the ages of 19 and 21.
Soon after the attack Jaish-e-Mohammad released a video, which was then aired on the India Today TV channel. In it, a young man identified as Adil Dar spoke about what he described as atrocities against Kashmiri Muslims. He said he joined the banned group in 2018 and was eventually “assigned” the task of carrying out the attack in Pulwama.
He also said that by the time the video was released he would be in jannat (heaven).
Dar is one of many young Kashmiri men who have been radicalised in recent years. On Thursday, main opposition leader Rahul Gandhi said that the number of Kashmiri men joining militancy had risen from 88 in 2016 to 191 in 2018.
India has been accused of using brutal tactics to put down protests in Kashmir – with thousands of people sustaining eye injuries from pellet guns used by security forces.
What’s the reaction?
“We will give a befitting reply, our neighbour will not be allowed to de-stabilise us,” said Prime Minister Modi.
Mr Gandhi and two former Indian chief ministers of Jammu and Kashmir all condemned the attack and expressed their condolences.
The attack has also been widely condemned around the world, including by the US and the UN Secretary General.
The White House called on Pakistan to “end immediately the support and safe haven provided to all terrorist groups operating on its soil”.
Pakistan said it strongly rejected any attempts “to link the attack to Pakistan without investigations”.
What’s the background?
There have been at least 10 suicide attacks since 1989 but this is only the second suicide attack to use a car.
Prior to Thursday’s bombing, the deadliest attack on Indian security forces in Kashmir this century came in 2002, when militants killed at least 31 people at an army base in Kaluchak near Jammu, most of them civilians and relatives of soldiers.
The latest attack also follows a spike in violence in Kashmir that came about after Indian forces killed a popular militant, 22-year-old Burhan Wani, in 2016.
More than 500 people were killed in 2018 – including civilians, security forces and militants – the highest such toll in a decade.
India and Pakistan have fought three wars and a limited conflict since independence from Britain in 1947 – all but one were over Kashmir.
Who are Jaish-e-Mohammad?
Started by cleric Masood Azhar in 2000, the group has been blamed for attacks on Indian soil in the past, including one in 2001 on the parliament in Delhi which took India and Pakistan to the brink of war.
Most recently, the group was blamed for attacking an Indian air force base in 2016 near the border in Punjab state. Seven Indian security personnel and six militants were killed.
It has been designated a “terrorist” organisation by India, the UK, US and UN and has been banned in Pakistan since 2002.
However Masood Azhar remains at large and is reportedly based in the Bahawalpur area in Pakistan’s Punjab province.
India has demanded his extradition from Pakistan but Islamabad has refused, citing a lack of proof.
CHINDIA ALERT: You'll be living in their world, very soon 