Archive for ‘winter’

02/05/2020

How a llama could hold the key to beating the coronavirus

  • An antibody engineered from the animal’s immune system was found to neutralise the virus that causes Covid-19
  • American and Belgian researchers hope the discovery may help protect humans from the deadly illness
Winter the lama (front) lives on a farm operated by Ghent University's Vlaams Institute for Biotechnology. Photo: Tim Coppens
Winter the llama (front) lives on a farm operated by Ghent University’s Vlaams Institute for Biotechnology. Photo: Tim Coppens

A Belgian llama could hold the key to producing an antibody that neutralises the coronavirus that causes Covid-19.

More studies and clinical trials are needed to see if it can be used in humans to treat Covid-19, but the team of American and Belgian scientists who engineered the antibody said they were encouraged by their preliminary findings, which will be published in the journal Cell next week.

Jason McLellan, from the University of Texas at Austin and co-author of the study, described it as one of the “first antibodies known to neutralise Sars-CoV-2”, the official name for the virus.

“With antibody therapies, you’re directly giving somebody the protective antibodies and so, immediately after treatment, they should be protected,” he wrote in a press release.

“The antibodies could also be used to treat somebody who is already sick to lessen the severity of the disease.”
Winter the llama produced antibodies that proved effective against the Sars-CoV-2 virus. Photo: Tim Coppens
Winter the llama produced antibodies that proved effective against the Sars-CoV-2 virus. Photo: Tim Coppens
The scientists have been working on coronaviruses – including severe acute respiratory syndrome (Sars) and Middle East respiratory syndrome (Mers) – for years.

In 2016 they injected the llama, named Winter, with Sars and Mers in the hope of developing a treatment for the diseases.

“I thought this would be a small side project,” said Dorien De Vlieger from Ghent University in Belgium, who helped to isolate antibodies against coronaviruses from the llamas.

China’s race for a Covid-19 vaccine hits a hurdle – no outbreak at home

1 May 2020

“Now the scientific impact of this project became bigger than I could ever expect. It’s amazing how unpredictable viruses can be.”

A llama’s immune system produces two types of antibodies when it detects pathogens, one similar to human antibodies and one that is about a quarter of the size.

The antibodies produced by Winter were found to be effective in targeting the Sars virus’s spike protein, which allows it to bind to human cells.

Chinese firm ready to make 100 million Coronavirus vaccine doses if trials are successful
This year they decided to test the antibodies Winter had produced during the Sars experiment to see if it could prove effective against Covid-19.

Although it did bind itself to the Sars-CoV-2 virus it did so “weakly”, so the team then linked two copies of the antibody together to make it bind more effectively.

Oxford vaccine effective in monkeys, heading for mass production in India

30 Apr 2020

“That was exciting to me because I’d been working on this for years. But there wasn’t a big need for a coronavirus treatment then. This was just basic research,” said Daniel Wrapp from the University of Texas, a co-author of the study.

The smaller type of antibodies produced by llamas, called single-domain antibodies or nanobodies, can be used in an inhaler, according to Wrapp.

“That makes them potentially really interesting as a drug for a respiratory pathogen because you’re delivering it right to the site of infection,” said Wrapp.

Researchers created an antibody dubbed VHH-72Fc (blue) that binds tightly to the Sars-CoV-2 spike protein (pink, green and orange), blocking the virus from infecting cells. Photo: University of Texas at Austin
Researchers created an antibody dubbed VHH-72Fc (blue) that binds tightly to the Sars-CoV-2 spike protein (pink, green and orange), blocking the virus from infecting cells. Photo: University of Texas at Austin
The researchers are preparing for more trials with hamsters or primates to further test the antibody, before taking it to human trials.
The main subject of the study, Winter the llama, is now four years old and lives on a farm operated by Ghent University’s Vlaams Institute for Biotechnologym which said it has around 130 other llamas and alpacas at the facility.
Source: SCMP
26/04/2020

China’s smog-prone Hebei saw pollution fall 15% from October-March

SHANGHAI (Reuters) – China’s smog-prone northern province of Hebei met its air quality targets by a big margin over the winter after concerted efforts to tackle emissions, a local official said on Sunday, without mentioning coronavirus-related factory shutdowns.

Average PM2.5 concentrations over the October-March period dropped 15% from a year earlier to 61 micrograms per cubic metre, while sulphur dioxide also fell by a third, said He Litao, vice-head of the provincial environmental bureau.

Most experts have attributed the significant decline in air pollution throughout China in the first quarter to the coronavirus outbreak and tough containment measures, which saw cities and entire  provinces locked down and sharply reduced traffic and industrial activity throughout the country.

With millions staying at home, concentrations of lung-damaging PM2.5 particles fell by nearly 15% in more than 300 Chinese cities in the first three months of 2020.

Shanghai saw emissions fall by nearly 20% in the first quarter, while in Wuhan, where the pandemic originated, monthly averages dropped more than a third compared to last year.

However, He of the Hebei environmental bureau attributed the local decline in pollution to the “conscientious implementation” of government decisions even in the face of unfavourable weather conditions.

According to a winter action plan published last year, 10 cities in Hebei were expected to cut lung-damaging small particles known as PM2.5 by 1%-6% compared to the previous year.

Despite the decline, average PM2.5 was still much higher than China’s official standard of 35 micrograms, and the recommended World Health Organization level of 10 micrograms.

Source: Reuters

20/04/2020

Euro zone trade surplus grows, with decline in China imports

BRUSSELS (Reuters) – The euro zone’s trade surplus with the rest of the world grew in February, with a decline in imports from China as well as sharply lower energy needs because of mild winter weather.

The unadjusted goods trade surplus grew to 23.0 billion euros ($25.1 billion) in February, compared with 18.5 billion euros a year earlier. Exports rose by 1.6%, while imports fell by 1.0%.

For China, which already had widespread coronavirus restrictions in place in February, exports from the European Union as a whole were slightly lower than in February 2019. However, imports were down by 8.1%, according to data on Eurostat’s website.

Energy imports as a whole also declined by 9.6% in February, when comparing Jan-Feb data issued on Monday and January data from a month ago. That translated into 10.1% lower imports from Russia and 5.9% less from Norway.

The trade surplus with the United States, by contrast, grew by 21% in the month as exports increased and imports declined. The persistent surplus in goods has been a source of transatlantic tension.

On a seasonally adjusted basis the euro zone trade surplus also rose to 25.8 billion euros in February from 18.2 billion euros in January. Exports were 1.8% higher month-on-month and imports 2.3% lower.

Source: Reuters

20/04/2020

Coronavirus: Chinese Super League team return home to Wuhan after 104 days abroad

Fans greated the team as they arrived in Wuhan via train
Fans greeted the team as they arrived in Wuhan via train

Chinese Super League team Wuhan Zall made an emotional homecoming after being unable to return for three months because of the coronavirus pandemic.

Players had initially stayed at their winter training camp in Spain when the virus peaked in Wuhan in January.

After a prolonged transit in Germany, they landed in Shenzhen on 16 March and underwent three weeks’ quarantine.

They were greeted by fans when they arrived in Wuhan by train on Saturday evening.

“After more than three months of wandering, the homesick Wuhan Zall team members finally set foot in their hometown,” the team said on the Twitter-like Weibo.

Fans, dressed in the team’s orange colours, sang and gave the players flowers as they arrived home for the first time in 104 days.

Players will now spend time with their families before training resumes.

The team had first left Wuhan in early January to start preparing for the Super League season.

By the time they arrived in Malaga, residents in Wuhan were living under strict lockdown measures, and there were no planes or trains in or out of the capital.

Coach Jose Gonzalez told Spanish media at the time that the players “are not walking viruses, they are athletes” and asked for them not to be demonised.

The Chinese Super League was set to begin on 22 February but it has been postponed.

Wuhan raised its official Covid-19 death toll by 50% on Sunday, adding 1,290 fatalities.

Source: The BBC

07/04/2020

Coronavirus: How China’s army of food delivery drivers helped keep country going during outbreak

  • Buying and paying for meals and supplies online was already second nature for many Chinese before the Covid-19 lockdown
  • The supply and delivery networks that were already in place were able to work with the authorities in cities like Wuhan
China’s established home delivery system played an important role in getting food and other necessities to residents during the Wuhan lockdown. Photo: EPA-EFE
China’s established home delivery system played an important role in getting food and other necessities to residents during the Wuhan lockdown. Photo: EPA-EFE
When Liu Yilin, a retired middle schoolteacher in Wuhan, first heard rumours of a

highly contagious disease

spreading in the central Chinese city he started to stock up on supplies such as rice, oil, noodles and dried pork and fish.

These preparations spared the 66-year-old from some of the early panic when 
the city went into lockdown in late January

and shoppers flooded to the markets and malls to snap up supplies.

But as time went on and with residents banned from leaving their homes, he became increasingly concerned about getting hold of fresh supplies of vegetables, fruit and meat until the nation’s vast network of delivery drivers came to the rescue.
“It was such a relief that several necessity purchasing groups organised by community workers and volunteers suddenly emerged on WeChat [a leading social media app] days after the lockdown,” Liu said. “China’s powerful home delivery service makes life much easier at a time of crisis.”

Hu Xingdou, a Beijing-based independent political economist said: “Home delivery played a very important role amid the coronavirus outbreak. To some extent, it prevented people from starving especially in cases when local governments took extreme measures to isolate people.”

According to Liu, people in Wuhan during the lockdown had to stay within their residential communities, with community workers guarding the exits.

Human contact was limited to the internet. Residents placed orders online with farmers, small merchants or supermarkets to buy daily necessities, and community workers helped distribute the goods from deliverymen.

Every morning, Liu passed a piece of paper with his name, phone number and order number to a community worker who would collect the items from a courier at the gate of the residential area.

Thanks to a high population density in urban areas, affluent labour force and people’s openness to digital life, China has built a well-developed home delivery network.

Extensive funding from technology companies has been invested in hardware infrastructure, software to improve logistics and big data and cloud computing to help predict consumers’ behaviour.

Mark Greeven, professor of innovation and strategy at IMD Business School in Lausanne, Switzerland, said: “Whether it is delivery of products, air parcels or fresh food or even medicine or materials for medical use, China has a very well developed system. Much better developed than I think almost any other places in the world.

“Well before the crisis, China had started to embrace digital technology in daily life whether it is in consumption, business, government and smart cities and use of third party payments. All of these things have been in place for a long time and the crisis tested its agility and capability to deal with peak demand.”

China’s e-commerce giants help revive sales of farm goods from Hubei

3 Apr 2020
According to e-commerce giant JD.com, demands for e-commerce and delivery services spiked during the outbreak of Covid-19, the illness caused by the new coronavirus.
It sold around 220 million items between January 20 and February 28, mainly grains and dairy products with the value of beef orders trebling and chicken deliveries quadrupling compared with a year ago.
Tang Yishen, head of JD Fresh, its fresh foods subsidiary, said: “The surge of online demand for fresh merchandise shows the pandemic helped e-commerce providers further penetrate into the life of customers. It also helped upstream farm producers to know and trust us.”
Meituan Dianping, a leading e-commerce platform, said its grocery retail service Meituan Instashopping reported a 400 per cent growth in sales from a year ago in February from local supermarkets.
The most popular items ordered between January 26 and February 8 were face masks, disinfectant, tangerines, packed fresh-cut fruits and potatoes.
The food delivery service Ele.me said that, between January 21 and February 8, deliveries of frozen food surged more than 600 per cent year on year, followed by a nearly 500 per cent growth in delivery of pet-care products. Fresh food deliveries rose by 181 per cent while drink and snack deliveries climbed by 101 per cent and 82 per cent, respectively. Ele.me is owned by Alibaba, the parent company of the South China Morning Post.
Chinese hotpot restaurant chain adapts as coronavirus fears push communal meals off the menu
E-commerce providers used the opportunity to show goodwill and improve their relationship with customers and partners, analysts say.
Sofya Bakhta, marketing strategy analyst at the Shanghai-based Daxue Consulting, said the food delivery sector had made significant headway in reducing physical contact during the outbreak.
Delivery staff left orders in front of buildings, in lifts or temporary shelters as instructed by the clients as most properties no longer allowed them inside.
Some companies also adopted more hi-tech strategies.
In Beijing, Meituan used self-driving vehicles to deliver meals to contactless pickup stations. It also offered cardboard boxes to be used as shields aimed at preventing the spread of droplets among its clients while they ate in their workplaces. In Shanghai, Ele.me employed delivery drones to serve people under quarantine in the most affected regions.
Some companies even “shared” employees to meet the growing labour demand in the food delivery industry that could not be satisfied with their ordinary workforce, Bakhta said.
More employees from restaurants, general retail and other service businesses were “loaned” to food delivery companies, which faced manpower shortages during the outbreak, according to Sandy Shen, senior research director at global consultancy Gartner.
“These arrangements not only ensured the continuity of the delivery service but also helped businesses to retain employees during the shutdown,” she said.
A delivery man takes a break between orders in Wuhan, central China, during the lockdown. Photo: AFP
A delivery man takes a break between orders in Wuhan, central China, during the lockdown. Photo: AFP
Mo Xinsheng became one such “on-loan” worker after customers stopped coming to the Beijing restaurant where he worked as a kitchen assistant.
“I wanted to earn some money and meanwhile help people who are trapped at home,” said Mo, who was hired as a delivery man.
But before he could start work he had to go through lengthy health checks before he was allowed into residential compounds.
He also had to work long hours battling the wind and cold of a Beijing winter and carrying heavy loads.
“I work about 10 hours every day just to earn several thousand yuan [several hundred US dollars] a month,” he said.
“Sometimes I almost couldn’t breathe while my hands were fully loaded with packages of rice, oil and other things.
“But I know I’m doing an important job, especially at a time of crisis,” Mo said, “It was not until then that I realised people have become so reliant on the home delivery system.”
Woman uses remote control car to buy steamed buns amid coronavirus outbreak in China
The delivery system has been improved by an effective combination of private sector innovation and public sector coordination, said Li Chen, assistant professor at the Centre for China Studies at Chinese University of Hong Kong.
“[In China,] government units and the Communist Party grass roots organisations have maintained fairly strong mobilisation capabilities to cope with emergencies, which has worked well in the crisis,” he said.
However, Liu, the Wuhan resident, said prices had gone up and vegetables were three times more expensive than they had been over Lunar New Year in 2019.
“There were few varieties that we could choose from, apart from potatoes, cabbage and carrots,” he said.
“But I’m not complaining. It’s good we can still get fresh vegetables at a difficult time. Isn’t it? After all, we are just ordinary people,” he said.
Source: SCMP
30/11/2019

Beijing embraces timely first snow

CHINA-BEIJING-SNOW-SCENERY (CN)

A child makes a snowman at the Palace Museum in Beijing, capital of China, Nov. 30, 2019. Beijing saw a snowfall Friday night. (Xinhua/Meng Dingbo)

BEIJING, Nov. 30 (Xinhua) — Beijing on Saturday was covered in white after experiencing the first snow this winter, which experts said was timely after a much-delayed snowfall in last year’s droughty winter.

The snow, which began Friday evening, reached the level of a blizzard in the outlying districts of Yanqing and Changping. In the city proper, the average precipitation was 3.1 millimeters, said the Beijing Meteorological Service.

“The first snowfall in Beijing this winter was most timely. Records show since 1961, Beijing’s average first winter snowfall happened exactly on Nov. 29,” said Guo Jinlan, a chief forecaster with the service.

The city’s first snow last winter did not fall until February this year.

Experts expect the snow to reduce the risks of wildfire and clean the air in Beijing, whose air pollution usually deteriorates in the winter season.

The city has issued an alert for icy roads and advised citizens to beware of health problems during the low temperature and windy weather after the snow.

Source: Xinhua

11/12/2018

Men ‘detained for burning low-quality coal’ in northern China amid winter crackdown

  • But county government denies environment department statement, saying the men were ‘criticised and educated’ for using the banned heating fuel

That is according to the local environment department, which said in a statement on Saturday that the men, both surnamed Zhao, were detained by police in Quyang, Hebei province, last week.

But later in the day, the local government denied the department’s statement, saying it was “misinformation” and that the authorities had only “criticised and educated the men who burned low-quality coal”.

The environment department’s statement was later removed from its official account on social network WeChat.

China’s push to clean up its toxic air saw many local governments across the north of the country rush through a coal ban last winter. But a shortage of natural gas to replace coal heating systems left many households shivering in freezing temperatures, forcing the authorities into a U-turn on the ban. Without a reliable energy supply, the ban was relaxed and people in low-income areas were instead asked to choose high-quality coal over the low-end product to reduce emissions.

Ahead of winter this year, Quyang – located about 230km south of Beijing – is one of the local governments in northern China that has again cracked down on heating fuel used by families and businesses with a total ban on low-grade coal since late October.

It vowed to put a stop to pollution caused by low-quality coal and sent 30 law enforcement officers to villages in the county without central heating in late November to check that people were sticking to the ban, according to a statement on the local government’s website.

“Anyone who burns low-quality coal and pollutes the air will be detained and their image will be broadcast on TV so that others can learn a lesson from them,” the Quyang government said on November 27.

Since then, county authorities have confiscated 1,147 tonnes of low-quality coal and warned 13 households that have burned it, according to the local government.

It is not the first time Chinese have been detained for burning low-end coal or other fuel that is prohibited. In early November, Quyang authorities detained a Xiguo man for five days after police found him burning grass and hay on a hillside in the village.

“The hay burning was producing a lot of smoke and polluting the air … so Quyang police decided to detain him for five days,” the local environment department said.

County police said the detention was in line with the Security Administration Punishment Act, which states that “residents who do not obey government regulations in emergency or special times shall be detained for up to 10 days”.

In a case last winter, a man in Kaifeng, in central Henan province, was detained for eight days in December for burning low-quality coal, according to Bianliang Evening Post.

Beijing has said it will be less severe with its pollution curbs this winter as it grapples with slower economic growth and the trade war with the United States.

Last winter, it imposed blanket bans on industrial production in the Beijing-Tianjin-Hebei region, which is often the worst affected by choking smog. But in September the environment ministry said it would let steel plants continue producing as long as their emissions met standards.

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